• Wissenschaftliche Publikationen

Veröffentlichungen der HSWT

Die chronologische Liste zeigt aktuelle Veröffentlichungen aus dem Forschungsbetrieb der Hochschule Weihenstephan-Triesdorf. Zuständig ist das Zentrum für Forschung und Wissenstransfer (ZFW).

  • Prof. Dr. Iris Augustin, Julia Gross, Daniel Baumann, Claudia Korn, Grainne Kerr, Tamara Grigoryan, Cornelia Mauch, Walter Birchmeier, Michael Boutros

    • Berechtigungen:  Peer Reviewed

    Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis (2013) Journal of Experimental Medicine 210 (9), S. 1761-1777. DOI: 10.1084/jem.20121871

    Cells of the epidermis renew constantly from germinal layer stem cells. Although epithelial cell differentiation has been studied in great detail and the role of Wnt signaling in this process is well described, the contribution of epidermal Wnt secretion in epithelial cell homeostasis remains poorly understood. To analyze the role of Wnt proteins in this process, we created a conditional knockout allele of the Wnt cargo receptor Evi/Gpr177/Wntless and studied mice that lacked Evi expression in the epidermis. We found that K14-Cre, Evi-LOF mice lost their hair during the first hair cycle, showing a reddish skin with impaired skin barrier function. Expression profiling of mutant and wild-type skin revealed up-regulation of inflammation-associated genes. Furthermore, we found that Evi expression in psoriatic skin biopsies is down-regulated, suggesting that Evi-deficient mice developed skin lesions that resemble human psoriasis. Immune cell infiltration was detected in Evi-LOF skin. Interestingly, an age-dependent depletion of dendritic epidermal T cells (DETCs) and an infiltration of γδlow T cells in Evi mutant epidermis was observed. Collectively, the described inflammatory skin phenotype in Evi-deficient mice revealed an essential role of Wnt secretion in maintaining normal skin homeostasis by enabling a balanced epidermal-dermal cross talk, which affects immune cell recruitment and DETC survival.
  • Stefan Hanke, V. Ditz, Markus Herrmann, Werner Back, Prof. Dr. Martin Krottenthaler

    La Influencia de Linalol y Productos Secundarios de la Fermentación sobre Aromas Indeseadas – Parte 1 (2013) Brauwelt en Español 03/2013 , S. 94-97.

  • Heinrich Rübsam, Thomas Becker, Prof. Dr. Martin Krottenthaler

    Optimierung der Sudhaustechnologie mit Dimethylsulfid als Leitkomponente (2013) Brauwelt chinesisch 03/2013 , S. 12-15.

  • Heinrich Rübsam, Prof. Dr. Martin Krottenthaler, Martina Gastl, Thomas Becker

    Influence of starch sources and mashing procedures on the range of Moelcular Weight Distribution (MWD) and the intensity of palate fullness of beer (2013) 34th Congress of the European Brewery Convention (EBC 2013), Proceedings of a meeting held 26-30 May 2013, Luxembourg .

  • M. Haid, F. Qian, Prof. Dr. Martin Krottenthaler, Thomas Becker

    Bestimmung der optimalen Bedingungen zur Milchsäureproduktion durch Lactobacillus amylolyticus (2013) Brauwelt International 30 (4), S. 232-235.

  • M. Haid, F. Qian, Prof. Dr. Martin Krottenthaler, Thomas Becker

    Bestimmung der optimalen Bedingungen zur Milchsäureproduktion durch Lactobacillus amylolyticus (2013) Brauwelt russisch 02/2013 , S. 68-72.

  • Dr. rer. nat. Thorsten Schön, Prof. Dr. Martin Stetter, Ana Maria Perfeito Tomé, Prof. Dr. Elmar W. Lang

    • Berechtigungen:  Peer Reviewed

    A new Physarum Learner for Network Structure Learning from Biomedical Data (2013) 6th International Conference on Bio-inspired Systems and Signal Processing (BIOSIGNALS 2013), 11.-14. Februar 2013, Barcelona .

  • Andreas Weger, Samir Binder, Prof. Dr. Winfried Ruß

    Kombinierter Ansatz zur Nutzung von Biertreber (2013) Brauwelt 153 (1/2).

Betreuung der Publikationsseiten

Zentrum für Forschung und Wissenstransfer - Lageplan in Weihenstephan an der HSWT

Kontakt

Hochschule Weihenstephan-Triesdorf
Zentrum für Forschung und Wissenstransfer
Gebäude H21
Am Staudengarten 9
85354 Freising

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